BDBM294373 US9586959, Compound 104::US9586959, Compound 24::US9586959, Compound 68

SMILES CNC1CN(C1)c1nc2ncc(Br)cc2n2cnnc12

InChI Key InChIKey=MMVBKZHQTLDYKG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 294373   

TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294373(US9586959, Compound 104 | US9586959, Compound 24 |...)
Affinity DataIC50:  36nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294373(US9586959, Compound 104 | US9586959, Compound 24 |...)
Affinity DataIC50:  130nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
C&C Research Laboratories

US Patent
LigandPNGBDBM294373(US9586959, Compound 104 | US9586959, Compound 24 |...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In DepthDetails US Patent